«Biology of Eating Behaviour»

18.06.2026 12:30 – 13:30

Using genetic approaches, we have shown that disruption of multiple genes in the leptin-melanocortin pathway can cause human obesity. These molecules regulate signaling through hypothalamic circuits which project widely throughout the brain. By coupling genetic, molecular and physiological studies we are discovering key regulators of human eating behaviour. Some of these molecules regulate anxiety/fear responses, social interaction and maternal care, demonstrating the critical role of these circuits in human innate behaviour.